Pneumomediastinum: A Brief Review Of Literature Apropos Of A Case Report


  • Flávia Fernandes Serviço de Radioterapia, IPO-Porto, Portugal
  • Gonçalo Paupério Serviço de Cirurgia Torácica, IPO-Porto, Portugal
  • Ana Rodrigues Serviço de Oncologia Médica



The authors present a case of a 72-year-old man diagnosed with pneumomediastinum in a positron emission tomography scan (18F-FDG PET-CT) to assess the tumor response to palliative chemotherapy. The patient was asymptomatic and had no special findings in physical examination. Conservative approach was decided by the multidisciplinary team. The patient had an uneventful recovery.


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Kouritas VK, Papagiannopoulos K, Lazaridis G, Baka S, Mpoukovinas I, Karavasilis V, et al. Pneumomediastinum. J Thorac Dis. 2015, 7(S1): S44-S49.

Macia I, Moya J, Ramos R, Morera R, Escobar I, Saumench J, et al. Spontaneous pneumomediastinum: 41 cases. Eur J Cardio- thorac Surg. 2007, 31:1110–4.

Al-Mufarrej F, Badar J, Gharagozloo F, Tempesta B, Strother E, Margolis M. Spontaneous pneumomediastinum: diagnostic and therapeutic interventions. J Card Surg. 2008, 3(59).

Caceres M, Ali SZ, Braud R, Weiman D, Garrett HE. Spontaneous Pneumomediastinum: A Comparative Study and Review of the Literature. Ann Thoracic Surg. 2008, 86:962– 6.

Sakai M, Hiyama T, Kuno H, Mori K, Saida T, Ishiguro T, et al. Thoracic abnormal air collections in patients in the intensive care unit: radiograph findings correlated with CT. Insights Imaging. 2020, 11:35.

Macklin MT, Macklin CC. Malignant intersticial emphysema of the lungs and mediastinum as an importante occult complication in many respiratory diseases and other conditions: an interpretation of the clinical literature in the light of laboratory experiment. Medicine 1944. Vols. 23, paragraph 4, 281-358.

Sadayuki M, Shinji G. Spontaneous pneumomediastinum and Macklin effect: Overview and appearance on computed tomography. World J Radiol. 2014, 28; 6(11): 850-854.

Grapatsas K, Tsilogianni Z, Leivaditis V, Kotoulas S, Kotoulas C, Koletsis E, et al. Hamman's syndrome (spontaneous pneumomediastinum presenting as subcutaneous emphysema): A rare case of the emergency department and review of the literature. Respir Med Case Rep. 2018, 63–65.

Meireles J, Neves S, Castro A, França M. Spontaneous pneumomediastinum revisited. Respir Med CME. 2011, 4(4): 181-183. 10. Sahni S, Verma S, Grullon J, Esquire A, Patel P, Talwar A. Spontaneous pneumomediastinum: Time for consensus. N Am J of

Med Sci 5. 2013, 460–464.




How to Cite

Fernandes F, Paupério G, Rodrigues A. Pneumomediastinum: A Brief Review Of Literature Apropos Of A Case Report. Rev Port Cir Cardiotorac Vasc [Internet]. 2022 Oct. 5 [cited 2024 Jun. 13];29(3):67-9. Available from:



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