Risk Of Venous Thrombosis In The Primary Care Setting During The Covid-19 Pandemic


  • Ana Azevedo-Cerqueira Family Medicine, USF Odisseia, Maia, Portugal
  • Pedro Torrão Pinheiro Family Medicine, USF Ponte Velha, Santo Tirso, Portugal https://orcid.org/0009-0009-0260-0070
  • Jaime Oliveira Family Medicine, USF Odisseia, Maia, Portugal https://orcid.org/0000-0002-2424-2392
  • Maria Manuel-Marques Family Medicine, USF Odisseia, Maia, Portugal
  • João Rocha-Neves Angiology and Vascular Surgery Department, Centro Hospitalar de São João, Porto, Portugal; Department of Biomedical sciences – Anatomy Unit, Faculdade de Medicina da Universidade do Porto, Portugal; Department of Surgery, Faculdade de Medicina da Universidade do Porto, Portugal https://orcid.org/0000-0002-2656-8935




Aims: This study aimed to evaluate the variability of risk factors among patients with lower limb venous thrombosis, either Deep Vein Thrombosis (DVT) or Superficial Vein Thrombosis (SVT) in community patients with recent or current SARS-CoV-2 infection compared to a historical cohort.

Methods: We performed a historical retrospective analysis of all patients who presented to a primary health care unit and were diagnosed with DVT or SVT from January 2020 to December 2021. Historic controls were selected from January 2018 to December 2019. Demographic and clinical data were collected, including BMI, use of oral combined contraception, smoking status and date of COVID-19 infection diagnosis. Univariate analysis was performed for data assessment, including Chi-Square and ANOVA tests.

Results: Of the 8547 patients who attended a non-programmed consultation in the timeframe, seventy-nine patients (0.9%) were diagnosed with DVT (19) or SVT (60) and were included in the study. Their mean age was 57.3 ± 15.93 years, with a female-to-male ratio of 3.2 to 1. There was no significant association between COVID-19 and the development of DVT or SVT (p=0.151). However, there was a trend observed indicating a shift in the predominant gender in patients diagnosed with these conditions (85% females in 2018 versus 53.8% in 2021; p=0.077).

Conclusions: Outpatients seen by general practitioners during the pandemic of COVID-19 appear to present a trend towards an increased risk of combined DVT and SVT compared with patients of a historical cohort. Further studies are necessary to shed some light on this issue since robust evidence enables clinicians and policymakers to minimize venous thromboembolism risk in patients with SARS-CoV-2 infection.


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How to Cite

Azevedo-Cerqueira A, Torrão Pinheiro P, Oliveira J, Manuel-Marques M, Rocha Neves J. Risk Of Venous Thrombosis In The Primary Care Setting During The Covid-19 Pandemic. Rev Port Cir Cardiotorac Vasc [Internet]. 2023 Apr. 4 [cited 2024 Jun. 13];30(1):43-7. Available from: https://pjctvs.com/index.php/journal/article/view/310



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