Descending Necrotizing Mediastinitis: A 7-Year Single-Centre Experience

Authors

  • Catarina Pereira Moita Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal https://orcid.org/0009-0001-4107-5856
  • Catarina Figueiredo Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • Zenito Cruz Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • Ana Inácio Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • Ana Rita Costa Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • João Maciel Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • João Santos Silva Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • João Eurico Reis Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal
  • Paulo Calvinho Thoracic Surgery Department – Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal

DOI:

https://doi.org/10.48729/pjctvs.564

Keywords:

Descending Necrotizing Mediastinitis, Surgical Drainage, Transcervical Drainage, Transthoracic Drainage, Thoracic Surgery

Abstract

Introduction: Descending necrotizing mediastinitis (DNM) is a life- threatening condition that originates from head and neck infections, subsequently extending into the mediastinum. Prompt diagnosis and emergent surgical intervention are critical for patient survival. This study aims to present our experience in managing DNM.

Methods: The present study retrospectively analyzed patients with DNM who underwent surgical treatment in our center, between 2017 and 2023.

Results: We identified 14 adult patients treated in our center in the 7- year period, with male predominance and a mean age of 45 years. The primary infection sites were pharyngeal in 7, cervical in 5 and odontogenic in 2 patients. At diagnosis, 4 patients had type I DNM, 3 had type IIA and 7 had type IIB. Disease progression to stage II occurred in the majority of patients (n = 12). A total of 34 cervical procedures and 20 thoracic surgeries were performed, with a median of 2 cervical [1- 7] and 1 thoracic [0- 3] interventions per patient. Combined cervicotomy and thoracotomy was the preferred surgical approach. There was a low rate of long- term morbidity and no mortality.

Conclusion: Successful management of DNM relies on early diagnosis trough computed tomography scan, appropriate antibiotic therapy, and urgent surgical drainage of the affected cervical and mediastinal planes. Our experience highlights favorable outcomes, underscoring the value of a well- coordinated multidisciplinary approach.

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Published

10-05-2026

How to Cite

1.
Moita CP, Figueiredo C, Cruz Z, Inácio A, Costa AR, Maciel J, et al. Descending Necrotizing Mediastinitis: A 7-Year Single-Centre Experience. Rev Port Cir Cardiotorac Vasc [Internet]. 2026 May 10 [cited 2026 May 11];33(1):25-32. Available from: https://pjctvs.com/index.php/journal/article/view/564

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