GIANT PLEURAL TUMOR AND SEVERE HYPOGLYCEMIA: DOEGE-POTTER SYNDROME IN A PREVIOUSLY HEALTHY FEMALE

Authors

  • Nádia Junqueira Serviço de Cirugia Cardiotorácica, Hospital Santa Maria, Lisboa, Portugal
  • João Caldeira Serviço de Cirugia Cardiotorácica, Hospital Santa Maria, Lisboa, Portugal
  • Ricardo Ferreira Serviço de Cirugia Cardiotorácica, Hospital Santa Maria, Lisboa, Portugal
  • Filipe Costa Serviço de Anestesia, Hospital Santa Maria Hospital, Lisboa, Portugal
  • Joana Silva Serviço de Cirugia Cardiotorácica, Hospital Santa Maria, Lisboa, Portugal
  • Teresa Monteiro Serviço de Anestesia, Hospital Santa Maria Hospital, Lisboa, Portugal
  • Ângelo Nobre Serviço de Cirugia Cardiotorácica, Hospital Santa Maria, Lisboa, Portugal

DOI:

https://doi.org/10.48729/pjctvs.38

Abstract

Introduction: Doege–Potter’s syndrome is a rare paraneoplastic syndrome, consisting in hypoglycemia and solitary fibrous tumor of the pleura. These tumors represent <5% of all pleural tumours and can only be cured by surgery. In this article, we report a case of a patient presenting with severe hypoglycemia, as the only symptom, and a mass occupying the entire left hemithorax.

Case presentation: A54 year old female with severe hypoglycemia, a chest radiography with almost total opacification of the left hemithorax and a computed tomography scan with a mass in the left hemithorax. Surgery was performed and a mass with 30cm × 18cm × 11cm weighing 3195g was resected. The postoperative course was uneventful with immediate resolution of the hypoglycemia. The immunohistochemistry diagnosis was solitary fibrous tumor of the pleura.

Conclusions: Solitary fibrous tumor of the pleura are very rare. Less than 5% are associated with hypoglycemia, taking the form of Doege-Potter Syndrome. Radiation therapy and chemotherapy have shown low response rate and complete surgical resection is the only procedure that offers cure. This case reports describes a rare giant solitary fibrous tumor of the pleura with severe hypoglycemia, successfully treated by surgery. Long-term follow-up of the patient after the surgery is necessary for detection of any possible recurrence.

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References

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Published

17-04-2021

How to Cite

1.
Junqueira N, Caldeira J, Ferreira R, Costa F, Silva J, Monteiro T, Nobre Ângelo. GIANT PLEURAL TUMOR AND SEVERE HYPOGLYCEMIA: DOEGE-POTTER SYNDROME IN A PREVIOUSLY HEALTHY FEMALE. Rev Port Cir Cardiotorac Vasc [Internet]. 2021 Apr. 17 [cited 2024 Mar. 28];27(3):223-6. Available from: https://pjctvs.com/index.php/journal/article/view/38

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Clinical Cases

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