SAFETY AND RISK FACTORS FOR THE MORBIDITY AND MORTALITY OF PNEUMONECTOMY: A RETROSPECTIVE 10- YEAR STUDY IN A SINGLE INSTITUTION

Authors

  • Joana Rei Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • Susana Lareiro Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • Pedro Fernandes Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • Patrícia Castro Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • Sara S. Costa Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • José Miranda Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • Luís Vouga Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal
  • Miguel Guerra Cardiothoracic Surgery Department, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal; Faculty of Medicine of the University of Porto, Oporto, Portugal

DOI:

https://doi.org/10.48729/pjctvs.32

Abstract

Objectives: Pneumonectomy is a procedure with high post-operative morbidity and mortality. This study aims to assess and identify possible risk factors that can affect post-operative outcome, therefore determining the safety of pneumonectomy in specific groups.

Methods: A total of 63 patients submitted to pneumonectomy at our centre, from February 2008 to February 2018, were included in our retrospective study. Age, gender, side of intervention, diagnosis, pre-operative symptoms, substance abuse and comorbidities were assessed. Early and late post-operative complications, as well as death were our major outcomes. We analysed the impact of preoperative variables on major outcomes using SPSS statistics.

Results: We found a 9,8% surgery-related mortality and 1-year survival rate of 76,2%. The incidence of early complications in our population was of 35% while eleven patients (17,4%) developed late post-operative complications. No statistical difference was found when comparing survival time between genders or age groups. Right sided pneumonectomies seem to be associated with an higher mortality risk. No other association between risk factors and outcomes reached statistical significance in both univariate and multivariate analysis.

Conclusions: Pneumonectomy is a viable option regardless of age whenever the patient has a good functional and cardiopulmonary status. Gender and diagnostic group do not seem to influence adverse event risk, although right- -sided pneumonectomies show an increased risk for post-operative death. Care should be taken with patients submitted to neoadjuvant therapy. All patients should be encouraged to cease smoking as early as possible before surgery, given the increased risks for post-operative complications.

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Published

17-04-2021

How to Cite

1.
Rei J, Lareiro S, Fernandes P, Castro P, Costa SS, Miranda J, Vouga L, Guerra M. SAFETY AND RISK FACTORS FOR THE MORBIDITY AND MORTALITY OF PNEUMONECTOMY: A RETROSPECTIVE 10- YEAR STUDY IN A SINGLE INSTITUTION. Rev Port Cir Cardiotorac Vasc [Internet]. 2021 Apr. 17 [cited 2024 Jun. 13];27(3):203-8. Available from: https://pjctvs.com/index.php/journal/article/view/32

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