BEST-CLI versus BASIL-2 Trial: Conflicting Results?


  • Joana Cruz Silva Vascular Surgery Associated Editor, Angiology and Vascular Surgery Department, Hospital Garcia de Orta, Portugal



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Conte, M.S., Bradbury, A.W., Kolh, P., White, J.V., Dick, F., Fitridge, R. et al. Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia. Eur J Vasc Endovasc Surg 2019;58(1):S1-S109.e33.

Adam D.J., Beard J.D., Cleveland T., Bell J., Bradbury A.W. et al. Bypass versus Angioplasty in Severe Isch- aemia of the Led (BASIL): Multicentre, Randomised Controlled Trial. Lancet 2005;3661925-1934.

Popplewell M.A., Davies H.O., Narayanswami J., Renton M., Sharp A. et al. A Comparison of Outcomes in Patients with Infrapopliteal Disease Randomised to Vein Bypass or Plain Balloon Angioplasty in the Bypass vs. Angioplasty in Severe Ischaemia of the Leg (BASIL) Trial. Eur J 118 Vasc Endovasc Surg 2017;54:195-201.

Farber A., Menard M.T., Conte M.S., Kaufman J.A., Powell R.J. et al. Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia. NEJM 122 2022;387:2305-2316.

Bradbury, A.W., Moakes, C.A., Popplewell M., Me cham L., Bate G.R. et al. A Vein Bypass First versus a Best Endovascular Treatment First Revascularisation Strate- gy for Patients with Chronic Limb Threate ing Ischemia who Required an Infra-popliteal, with or without an Additional More proximal Infra-inguinal Revascularization Procedure to Restore Limb Perfusion (BASIL-2): An Open label, Randomised, Multicentre, Phase 3 Trial. Lancet 2023; 401:1798-1809.

Popplewell M.A., Davies H.O., Renton M., Bate G., Deeks J.J. et al. Comparison of Outcomes Following Infrapopliteal Pain Balloon Angioplasty in the BASIL Trial (1999-2004) and in a Contemporary Series (2009- 2013). Vasc Endovasc Surg 2020;54:141-146.




How to Cite

Cruz Silva J. BEST-CLI versus BASIL-2 Trial: Conflicting Results?. Rev Port Cir Cardiotorac Vasc [Internet]. 2023 Jul. 7 [cited 2024 May 22];30(2):11-2. Available from:



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